Kan man höja kalciumhalten i bananflugor?
Postat: 09 dec 2009, 16:34
.... nej, tydligen inte.
Jag har inte läst den själv, men denna artikel ska tydligen visa på just det.
Calcium homeostasis in larval and adult Drosophila melanogaster
K.A. Dube, D.G. McDonald, M.J. O'Donnell *
Department of Biology, McMaster University, Hamilton, Ontario, Canada
Keywords
calcium homeostasis; Malpighian tubule; Drosophila; diet; epithelial transport
Abstract
Calcium homeostasis in Drosophila melanogaster was examined in response to the challenges imposed by growth, reproduction and variations in dietary calcium content. Turnover time for calcium, calculated as the time for 45Ca2+to accumulate to half the steady state value of 3.46 nmol/fly, was 3.3 days. Although larvae weighed 2× as much as adults, they contained 3-4× as much calcium. Anterior Malpighian tubules (Mts) contain much more calcium than posterior Mts, accounting for 25-30% of the calcium content of the whole fly. In response to a 6.2-fold increase in dietary calcium level, calcium content of whole flies increased only 10%. Hemolymph calcium concentration (0.5 mM) was similar in males and females and in animals raised on diets differing in calcium content. Fluid secretion rate, secreted fluid calcium concentration, and transepithelial calcium flux in tubules isolated from flies raised on high and low calcium diets did not differ significantly. Malpighian tubules secrete calcium at rates sufficient to eliminate whole body calcium content in 0.5 and 3 days for tubules secreting fluid at basal and maximal rates, respectively. It is suggested that flies absorb high quantities of calcium from the diet and maintain homeostasis through the combined effects of elimination of calcium in fluid secreted by the Malpighian tubules and the sequestration of calcium in granules, especially within the distal segment of the anterior pair of Malpighian tubules.
Här är ett citat från artikeln hämtat från: http://frogroom-podcast.blogspot.com/se ... results=50
Flies were raised on the standard calcium diet and then transferred to either the high calcium or low calcium diet within 24 h of emergence. Calcium contents of whole flies and tubules were measured for 10 days after transfer, and calcium contents of whole flies of the resulting F1 generation were determined at intervals for 15 days after emergence. The flies maintained a calcium content of ~4.4 nmol/fly for 10 days after emergence; there was no increase in calcium content with time after transfer to high calcium diet.
Jag har inte läst den själv, men denna artikel ska tydligen visa på just det.
Calcium homeostasis in larval and adult Drosophila melanogaster
K.A. Dube, D.G. McDonald, M.J. O'Donnell *
Department of Biology, McMaster University, Hamilton, Ontario, Canada
Keywords
calcium homeostasis; Malpighian tubule; Drosophila; diet; epithelial transport
Abstract
Calcium homeostasis in Drosophila melanogaster was examined in response to the challenges imposed by growth, reproduction and variations in dietary calcium content. Turnover time for calcium, calculated as the time for 45Ca2+to accumulate to half the steady state value of 3.46 nmol/fly, was 3.3 days. Although larvae weighed 2× as much as adults, they contained 3-4× as much calcium. Anterior Malpighian tubules (Mts) contain much more calcium than posterior Mts, accounting for 25-30% of the calcium content of the whole fly. In response to a 6.2-fold increase in dietary calcium level, calcium content of whole flies increased only 10%. Hemolymph calcium concentration (0.5 mM) was similar in males and females and in animals raised on diets differing in calcium content. Fluid secretion rate, secreted fluid calcium concentration, and transepithelial calcium flux in tubules isolated from flies raised on high and low calcium diets did not differ significantly. Malpighian tubules secrete calcium at rates sufficient to eliminate whole body calcium content in 0.5 and 3 days for tubules secreting fluid at basal and maximal rates, respectively. It is suggested that flies absorb high quantities of calcium from the diet and maintain homeostasis through the combined effects of elimination of calcium in fluid secreted by the Malpighian tubules and the sequestration of calcium in granules, especially within the distal segment of the anterior pair of Malpighian tubules.
Här är ett citat från artikeln hämtat från: http://frogroom-podcast.blogspot.com/se ... results=50
Flies were raised on the standard calcium diet and then transferred to either the high calcium or low calcium diet within 24 h of emergence. Calcium contents of whole flies and tubules were measured for 10 days after transfer, and calcium contents of whole flies of the resulting F1 generation were determined at intervals for 15 days after emergence. The flies maintained a calcium content of ~4.4 nmol/fly for 10 days after emergence; there was no increase in calcium content with time after transfer to high calcium diet.